Syphilis Symptoms in Men & Women | How to Recognize Syphilis Symptoms . Syphilis is a sexually transmitted disease (STD) caused by the Treponema pallidum bacteria. The proper syphilis treatment is antibiotics. One of the challenges is that syphilis symptoms mimic many other diseases and infections, and many infected individuals may not be aware they have it. Syphilis is a lifelong illness unless antibiotic medication kills the infection.
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