Alzheimer’s disease – plaques, tangles, causes, symptoms & pathology

Alzheimer’s disease – plaques, tangles, causes, symptoms & pathology

What is Alzheimer’s disease? Alzeimer’s (Alzheimer) disease is a neurodegenerative disease that leads to symptoms of dementia. Progression of Alzheimer’s disease is thought to involve an accumulation of beta-amyloid plaque and neurofibrillary tangles in the brain. Subscribe – More videos – Support us on Patreon –

This video covers the mechanisms and pathophysiology thought to contribute to Alzheimer’s disease, including a definitions of sporadic as well as familial Alzheimer’s, common signs and symptoms, and diagnosis.

Subscribe –

This video is brought to you by Osmosis. Along with providing open-access videos, Osmosis offers a comprehensive e-learning platform that connects med students with thousands of flashcards and quiz questions, depending on each student’s needs. Ever wish information would just diffuse into your brain? Well, Osmosis helps make that possible—don’t learn it, osmose it!

Support us on Patreon! –

We also have free practice questions for the USMLE and NCLEX-RN exams here:

Also, we’re social:

Facebook –
Twitter –

Got feedback? We’d love to hear it!

This video is licensed under a Creative Commons CC-BY-SA 4.0 international license, which means that you’re free to share and adapt it so long as you follow the Attribution and ShareAlike terms and conditions!


Script/audio/visuals: Tanner Marshall, MS
Reviewer: Rishi Desai, MD, MPH

Beta amyloid plaque histology by ‘Jensflorian’ –
Neurofibrillary tangles histology by ‘Nephron’ –,_HE_4.JPG
Sword slash attack sound effect by Iwan Gabovitch –
Cargo train sound effect by Stephan Schutze –

Please follow us: